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KMID : 1035520140020020119
Brain Tumor Research and Treatment : BTRT
2014 Volume.2 No. 2 p.119 ~ p.123
Hemorrhagic Recurrence in Diffuse Astrocytoma without Malignant Transformation
Baek Hyun-Joo

Kim Seong-Min
Chung Seung-Young
Park Moon-Sun
Abstract
Although uncommon, hemorrhage can be a complication of low grade glioma with an unfavorable prognosis such as transformation to higher grade glioma. To our knowledge, hemorrhagic recurrence of World Health Organization Grade II, diffuse astrocytoma without malignant transformation has not been reported. Thus, we report a case of diffuse astrocytoma with hemorrhagic recurrence without malignant transformation. The patient had undergone craniotomy and tumor removal 7 years previously. Annual follow-up MRIs had shown evidence of slow tumor recurrence. With the sudden onset of seizure, the patient was diagnosed as hemorrhagic recurrence and underwent second tumor removal highly suspecting malignant change into higher grade glioma. Histopathology confirmed diffuse astrocytoma without malignant changes. As the patient¡¯s postoperative condition was excellent, we plan to withhold chemotherapy and radiation therapy for use as a later treatment option.
KEYWORD
Astrocytoma, Glioma, Recurrence
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